Specifically, Boston leads the way in embracing new research models (for example, Research at the Broad Institute of Harvard and MIT) and, in building a new research culture that has strong roots in academia and the pharma sector. A recent contribution of US$650 million as the philanthropic donation to Broad is the true testimony. It would be nice to see efforts like this in a country like India, who are aspiring to be a powerhouse in building ‘knowledge-based economy’.
5.0 Advancements in technology
Beyond the current approaches taken in the onset of drug development, a major defining factor for research and development in the bioengineering and pharmacological fields includes the use of sufficient equipment. Turning to tools which help them perform accurate measurements and assessment of drug candidates has transformed the way biomedical researchers approach pharmaceutical development, allowing for results that are both more rapid and more precise.
Current technological advancements include artificial intelligence (AI) supercomputing, hands-off automation, computer-aided gene writing and editing, buffer screening, and high-resolution stability data resources. While considered cutting-edge at the time, the archaic computer systems used by the scientific community were largely immature in the past, and their associated technology was understandably insufficient. However, today’s more modern computing has paved the way for increased reliability, allowing for the improved facilitation of this much-needed R&D.
One such tool includes the NanoTemper Prometheus system. Through it, researchers can utilize a variety of valuable technological resources, making it possible for them to better interpret key considerations. These include variables such as particle sizing, aggregation, and thermal unfolding. As the new gold standard for protein stability characterization, drug development and discovery is made easier with Prometheus. And in turn, the outcome can be considered more trustworthy in the long run, ensuring better health and a more positive outlook for those in need.
