Ion channels have been excellent drug discovery targets for decades with clinically meaningful drugs identified targeting sodium channels, including (e.g. lamotrigine), calcium channels (e.g. amlopdipine), GABA receptors (e.g. diazepam) and ATP-gated potassium channels (e.g. glipizide) and several others. However, new ion channel modulators have not been emerging at a rapid pace in the recent years, […]
pharmaceutical industry
Redesigning Drugs
As a medication becomes widely used, new insights emerge on modes of action, side effects and patient response. At the same time, advances in molecular biology, receptor pharmacology and better understanding of the clinical condition may create possibilities for new indications or for better treatment of the existing indication by altering dosage regimen or by […]